Centre For Bone Marrow Transplant+91-11-30403040
The Umbilical Cord Blood Transplant Unit at BLK-Max Super Speciality Hospital consistently aims at providing quality health assistance in order to improve the lives of patients requiring treatment for blood related disorders.
The comprehensive patient care we offer is at par with international guidelines. We follow a patient-centric treatment plans using cutting-edge technologies, innovative techniques and methodologies.
Umbilical cord blood is one of the richest sources of stem cells and extensively utilised for transplantation. In this type of transplant stems cells are reserve from umbilical cord blood. The source of umbilical cord blood is the umbilical cord retrieve after the birth of the baby. This cord blood is processed and freeze for future use in cord blood transplant.
Although cord blood cells have fewer stem cells as compare to other transplants but hold a high tendency of growing more blood cells inside the body than those present in bone marrow. The benefit of using Umbilical cord blood transplant is that the immune cells in cord blood are still "naive", which means they are not yet active in attacking other cells and are less likely to attack the tissues of the transplant recipient and thus they are not necessary to be a close match.
There are various serious health conditions which require Umbilical cord blood transplant as a cure. Such illnesses include:
Umbilical cord blood transplantation is a process of replacing old cells line with new cells lining and help in replacing maligned cells or invigorate the system of new cells production.
Step 1: Pre-transplant Process: To ensure high safety and better outcomes your doctor might ask to perform some Pre-transplant tests and procedures. These tests include complete health checkup, to ensure that the patient’s body is ready to undergo the transplant procedure.
Step 2: Conditioning Process: After the completion of these tests, a patient has to undergo the Stem Cell Transplant Conditioning process. This process involves either chemotherapy or radiotherapy or a combination of is used to destroy the diseased cells. The conditioning process helps in:
Step 3: Umbilical cord blood Transplant: The patient undergoes cytotoxic treatment where the harvested and processed stem cells are transplanted into the patient using a central venous catheter. These stem cells then travel through the bloodstream of the patient into the different places inside the bones. The transplant offers high tendency to a patient to create new blood cells.
Step 4: Engraftment: In this process, the patient is under the close monitoring for the sign of the growth of new stem cells along with supportive care.
Step 5: Post Engraftment monitoring and continuation of immunosuppression
A patient must take care of some of the very important precautions before and after the transplantation process, which includes:
Before the Transplantation:
After the Transplantation:
Generally, a patient receives high doses of chemotherapy or radiation therapy before a transplant, which come with complications such as
Other complications due to transplant include:
Studies have proved that there are fewer complications in Umbilical cord blood transplantation as compared to the different type of transplants. However, it is the most useful type of transplant as there is no need to match the cord blood closely to the patient's blood. Thus it serves an option for a patient with uncommon tissue types.
Dr. Pawan Kumar Singh
Centre For Bone Marrow Transplant
Dr. Megha Verma
Centre For Bone Marrow Transplant