Director
Haemato-oncology and Bone Marrow Transplant
+91-11-30403040Bone Marrow Transplant Centre at BLK-Max super speciality hospital is one of the largest bone marrow transplant centres in India. We offer specialist services to patients across a wider catchment area. The Centre aims to deliver advanced patient care, supported by a team of expert surgeons, haematologists, doctors and nurses for providing advanced Bone marrow transplant treatment services with excellent patient outcomes.
Autologous means cells acquired from the patient’s body, who is the donor and the receiver simultaneously. An autologous transplant is usually done on the patient using his/her own bone marrow or stem cells.
The autologous stem cell transplant process can be done either by using bone marrow harvesting or peripheral blood stem cells:
The next step is to process the harvested Bone marrow/ stem cells.
Body Location- Generally bone marrow is harvested from hip bone, pelvis and sternum.
Alternate name- Autologous Bone marrow transplant is also known as Autologous Stem cell transplant.
There are various serious and often fatal illnesses that require bone marrow transplant as a cure. Such illnesses include:
Cancerous Illnesses (80% Of Cases) - Autologous Bone Marrow Transplant is done in relapsed/ refractory cancers. Lymphoma, myeloma and other cancers of the blood, like cell lymphoma and AML.
Non-Malignant Illnesses -These illnesses include a condition where the bone marrow stops functioning, consequently to hepatitis or poisoning or with no evident cause. This category also involves conditions where the creation of a certain type of red blood cell is disrupted, such as thalassaemia or drepanocytosis. It also includes severe infant immunodeficiencies or hereditary diseases.
Since it’s a crucial treatment process, a patient has to undergo various processes before the autologous bone marrow transplant to ensure high safety and better outcomes.
Step 1: Pre-Transplant Process: A doctor might prescribe Pre-transplant tests and procedures, where a series of tests and procedures are performed to ensure the patient’s general health and the status of the medical condition. This process of evaluation may take several days.
Step 2: Conditioning Process: After completing the medical evaluation, a patient has to undergo the conditioning process. In this process, either chemotherapy or radiation therapy or a combination of both is given to the patient to:
Step 3: Autologous Bone Marrow Transplant: A patient now has to go through cytotoxic treatment, which involves the transplantation of the harvested and processed cells back into the patient's body through a central venous catheter. These cells then travel through the bloodstream into the places inside the bones, where they tend to create new bone marrow.
Step 4: Engraftment: In this process, the patient is under close monitoring for the sign of the growth of new stem cells along with supportive care.
Follow up
After the autologous bone transplant process, the patient will stay in the hospital or visit the hospital. At every follow-up, patients are monitored for side effects, weakness and other symptomatic treatment. Blood counts may fluctuate in the initial 3-4 weeks after autologous BMT.
Some of the precautions a patient must follow before and after the transplantation process include:
Before The Autologous Bone Marrow Transplantation:
After The Autologous Bone Marrow Transplantation:
Generally, a patient receives high doses of chemotherapy or radiation therapy before a transplant, which comes with complications such as:
Other complications due to transplant include:
The success rate of autologous bone marrow transplant is very high as it is the safest transplantation with very less complications involved.
The purpose of an autologous stem cell transplant is to allow for the delivery of high-dose chemotherapy or radiation therapy, which can destroy cancer cells. The reinfusion of the collected stem cells helps replenish the patient's blood and immune system.
Autologous stem cell transplant alone is not considered a curative treatment for cancer. It is typically used as part of a comprehensive treatment plan, along with chemotherapy or radiation therapy, to control or eliminate cancer cells in a very effective way.
The cost of autologous bone marrow transplant in Delhi can vary depending on several factors, including the hospital, medical team, duration of hospital stay, and required supportive care. It is advisable to consult with the healthcare provider or hospital for accurate cost information based on the individual case.
The recovery period after an autologous bone marrow transplant varies from person to person. It may take several weeks to months for the bone marrow to recover and for the immune system to regain strength. The medical team in Delhi will provide post-transplant care and support to facilitate the recovery process.
An autologous stem cell transplant is not a surgery in the traditional sense. It involves a series of procedures to collect, store, and reinfuse the patient's stem cells, but it does not typically involve invasive surgical procedures.IT is medical treatment.
Dr. Sanjeev Kumar Sharma
Haemato-oncology and Bone Marrow Transplant
Dr. Pawan Kumar Singh
Centre For Bone Marrow Transplant
Dr. Megha Verma
Centre For Bone Marrow Transplant
Dr. (Maj) Ravi Shankar
Paediatric Haematology
Dr. Akash Khandelwal
Haematology Oncology and Bone Marrow Transplant