Allogeneic transplantation is a process that offers great chances of curing the disease related to blood and bone marrow cancers and other disorders. In order to ensure high safety and better outcomes some preparation is made by the doctor before the surgery which a patient must follow.
Step 1: Pre-transplant Process: A patient has to take a series of Pre-transplant tests and procedures, to ensure their general health and the status of the current medical condition. This process of evaluation may take several days.
- Beginning Medical Evaluation
- Conference For Treatment Plan
- Central Venous Catheter Evaluation And Insertion
- Bone-Marrow/Stem Cells Harvest
Step 2: Conditioning Process: After the completion of the medical evaluation, a patient has to undergo the conditioning process. In this process either chemotherapy or radiation therapy or a combination of both is given to the patient to:
- Destroy any type of cancer cells in case of malignancy
- Preparing the patient’s bone marrow for the growth of new stem cells.
- Suppressing the patient's immune system
Step 3: Allogeneic Transplant: The patient undergoes cytotoxic treatment where the harvested and processed bone marrow/Stem cells are transplanted into the patient using a central venous catheter. The liquid bone marrow/stem cells travel through the bloodstream of the patient into the different places inside the bones. The transplant offers a patient’s body with a tendency to create new blood cells in a process known as engraftment.
Step 4: Engraftment: In this process, the patient is under the close monitoring for the sign of the growth of new stem cells along with supportive care.
Step 5: Post Engraftment monitoring and continuation of immunosuppression