Dr. Vikash Kumar
Sr. Consultant
BLK Cyberknife Centre
BLK Super Speciality
Hospital, New Delhi

Sound Treatment That Revives Hope

Cyberknife Radiosurgery in a case of Bilateral
Acoustic Neuroma


A 43 year old male from Nigeria, a known Hypertensive, was admitted to BLK Super Speciality Hospital, New Delhi with a history of diminished hearing from the left ear and gait instability. On evaluation, the MRI brain revealed extra-axial mass in bilateral cerebello-pontine (CP) angle with mass effect in left side and upstream ventricular dilatation, suggestive of Acoustic Neuroma. He underwent decompression surgery in 2010 in Nigeria. He was advised for Radiosurgery but could not undergo the same due to logistic reasons. He was well until May 2016 when he suddenly experienced severe headache. The MRI revealed increase in the size of lesion with hydrocephalus. Subsequently, he underwent VP shunt placement in June 2016 followed by microsurgery for the left CP angle tumour in July 2016 elsewhere. After surgery he developed diminished vision in both the eyes, facial deviation and incomplete closure of the left eye.

He was brought to BLK in April 2017. On examination, his higher mental functions were normal with ataxia and left sided facial palsy. The MR scan showed heterogeneously enhancing mass lesions in the B / L cerebello-pontine angle cistern extending to the B / L internal auditory meatus causing indentation of the brain stem, pons and extending along the dural margin to the premedullary cistern. The pure tone audiometry showed moderate to severe sensori-neural hearing loss in left side and moderate sensory neural hearing loss in the right side.


He was planned for Cyberknife Radiosurgery for the right CP angle mass to be followed by interval Cyberknife treatment for the left side CP angle mass after 6 months. After informed consent, the patient was taken for treatment planning. An orfi t uniframe was fabricated for immobilisation and reproducibility. The simulation was carried out with CT scan and MR Image fusion was done for target and organs at risk of delineation. A dose of 1650 cGy in 3 fractions was prescribed at 80% isodose level covering 95% of the target volume (GTV). The treatment planning was performed on MultiPlan® ver. 4.6 as per the prescribed dosage and OARs constraints. The dose to 95% of the GTV was 1651 cGy with conformity index (CI) 1.14 and homogeneity index 1.27. The beams were planned in such a manner that there was no entry or exit beams from the eyes and the dose fall off to the brain stem and right cochlea were well below the tolerance limit.


The patient withstood the treatment very well and there was no acute treatment related complication. He was sent back to his country on the next day of the treatment.